KWXY, AM 1340, Cathedral City

City Wide Ex Am Coming

Ddh154 1333..1340

Down syndrome (DS) is the most common chromosomally caused form of mental retardation and is caused by trisomy of chromosome 21. The over-expression of genes located on the trisomic region has been assumed to be responsible for the phenotypic abnormalities of DS, but this hypothesis has not been confirmed fully and the very existence of gene dosage effects has been called into question. We have...

Dmd058107 1334..1340

Anticancer agent 6-mercaptopurine (6MP) has been in use since 1953 for the treatment of childhood acute lymphoblastic leukemia (ALL) and inflammatory bowel disease. Despite being available for 60 years, several aspects of 6MP drug metabolism and pharmacokinetics in humans are unknown. Molybdoflavoenzymes such as aldehyde oxidase (AO) and xanthine oxidase (XO) have previously been implicated in ...

RPMv126n4-original article-1340.indd

Sao Paulo Med J. 2008;126(4):220-2. O R IG IN A L A R T IC L E José Eduardo Vasconcelos Fernandes Maria Isete Fares Franco Reinaldo Kenji Suzuki Nelson Mattos Tavares Sansom Henrique Bromberg Intestinal metaplasia in gallbladders: prevalence study Postgraduate program for surgical gastroenterology, Hospital do Servidor Público Estadual de São Paulo, São Paulo, Brazil CONTEXT AND OBJECTIVE: Gall...

Dmd064717 1336..1340

Minipigs represent a good animal model because of the physiologic and anatomic similarities they share with humans. Three cytochrome P450 (CYP) 3A isozymes, CYP3A22, CYP3A29, and CYP3A46, have recently been reported to be expressed in Bamaminipigs, which have limited data relating to their metabolic characteristics. In the present study, Bama minipig CYP3A22, CYP3A29, and CYP3A46 were recombina...